Introduction: Musculoskeletal problems are the common complaints of patients refer to internal medicine clinics and the pain is the most important of them. There are different physiotherapy methods for reduction of pain and action potential simulation therapy (APS therapy) is one of newest methods. The aim of this study was to determine reduction of pain with APS therapy. Materials & Methods: In 47 patients with different musculoskeletal pain APS therapy performed in 6 days each for 16 minutes and with current of 0.7-1.2 mA. Pain (VAS), Global functional status (ACR) and relief of pain (VAS) before and after study compared.Results: APS therapy reduced pain (p<0.001) and increased Global functional status (p<0.001) and increased relief of pain (p<0.005) but there was not any correlation between this reduction of pain with APS therapy and educational status and past history of physiotherapy and duration of illness in these patients.Conclusion: APS therapy is a useful physiotherapy modality for reduction of pain in musculoskeletal problems.

Introduction: Ionic channel rearrangements through the demyelinated axons or supporting media play significant role in remission of the neurological deficit in MS patients. In this study the effects of Verapamil as a calcium channel blocker on central conduction have been investigated through the evaluation of changes in P100 latency of the visual evoked potential.Method: This randomized double blinded, placebo-controlled, clinical trial was performed on two groups of 20 multiple sclerosis patients who had been diagnosed for definite MS and had no relapse during the last year. Case group received oral Verapamil, 40 mg, every 8 hours and was compared to Placebo group for changes in P100 latency.Results: In the Verapamil group, the P100 latencies showed an average decrease of 5ms comparing to the placebo group (6.1±4ms vs1 ± 0.5 ms). Verapamil had no significant effect on the VEP duration.Discussion: The present study suggests that pharmacological manipulation of calcium-dependent process, possibly at the level of demyelinated axon, can acutely facilitate central conduction of electrical impulses in some patients with clinically stable multiple sclerosis.

Due to the stochastic nature of wind energy, allocating an appropriate investment incentive for wind generation technology (WGT) is a complicated issue. We propose an improvement on the traditional incentive, known as capacity payment mechanism (CPM), to reward the wind generators based on their performance exogenously affected by the wind energy potential of the location where the turbines are installed, and therefore, lead the investments towards locations with more generation potential. In CPM, a part of investment cost of each generator is recovered through fixed payments. However, in our proposal, wind generators are rewarded according to dynamic forecasts of the wind energy potential of the wind farm where they are located. We use an auto-regressive moving average (ARMA) model to forecast the wind speed fluctuations in long-term while capturing the auto-correlation of wind velocity variation in consecutive time intervals. Using the system dynamics (SD) modelling approach a competitive electricity market is designed to examine the efficiency of the proposed incentive. Performing a simulation analysis, we conclude that while a fixed CPM for wind generation can decrease the loss of load durations and average prices in long-term, the proposed improvement can provide quite similar results more efficiently.

Background: Radial keratotomy is a major type of refractive surgery. This study was performed to determine the association of visual evoked potential (VEP) and radial keratotomy. Materials and methods: In this cross-sectional descriptive-comparative survey, 25 patients under radial keratotomy attending to Basir Clinic in 2014 and 2015 were enrolled and the VEP results, including voltage and latency, were determined and compared with 25 control subjects. Results: The mean voltage was 5.6 ± 2.0 microvolt and 6.0 ± 2.2 microvolt in case and control groups, respectively (P>0.05). Mean latency duration was 95.7 ± 6.1 millisecond and 95.6 ± 5.7 millisecond in case and control groups, respectively (P>0.05). Conclusion: Totally, according to the obtained results, it may be concluded that there is no significant association between visual evoked potential and radial keratotomy. Keywords: VEP, Refractory surgery, Radial keratotomy.

In this paper, recommended spiral passive micromixer was designed and simulated. spiral design has the potential to create and strengthen the centrifugal force and the secondary flow. A series of simulations were carried out to evaluate the effects of channel width, channel depth, the gap between loops, and flowrate on the micromixer performance. These features impact the contact area of the two fluids and ultimately lead to an increment in the quality of the mixture. In this study, for the flow rate of 25 μl/min and molecular diffusion coefficient of 1×10-10 m2/s, mixing efficiency of more than 90% is achieved after 30 (approximately one-third of the total channel length). Finally, the optimized design fabricated using proposed 3D printing method.

Purpose: To evaluate the power of two methods of potential acuity pinhole (PAP) and illuminated near card (INC) in prediction of final visual acuity after cataract surgery.Materials and Methods: This sequential double blind cross-over clinical trial was performed on 100 eyes of 100 patients. The patients were classified into 3 groups in terms of best corrected visual acuity (BCVA): I-BCVA ≥ 20/50, II-BCVA of 20/60-20/200, and III-BCVA of less than 20/200 to a minimum of 20/400. Potential visual acuity with the two methods (PAP and INC) was predicted before surgery. Eight weeks after cataract surgery, far BCVA was evaluated and the two methods were compared.Results: Mean age of the patients was 65 years (range 30-90). Prediction power of PAP test in groups I, II, and III was 75%, 91.7%, and 73.6%, respectively. Prediction power of INC test in groups I, II, and III was 75%, 87.5%, and 80.6%, respectively. Linear relationship between PAP and post operative far BCVA (R) was 0.71 and far INC was 0.51 (regression analysis, P<0.0001). Linear relationship of PAP method and post operative far BCVA in INC method were: Far Log n = -0.12+0.52 PAP Log n and Far Log n = -0.267+0.44 INC Log n, respectively.Conclusion: Prediction powers for visual acuity in PAP test and INC test were nearly equal. Not considering the preoperative BCVA, both methods had the required power for prediction of visual acuity.